Summary: Visual cortical plasticity is high during early life. but gradually decreases with development. This is due to the Otx2-driven maturation of intracortical inhibition that parallels the condensation of extracellular matrix components into perineuronal nets mainly around parvalbumin-positive GABAergic neurons. Repressor Element 1 Silencing Transcription (REST) epigenetically co... https://hollandscountryclothinges.shop/product-category/swiss-army-knives/