Abstract Brain metastasis (BM) predominantly occurs in triple-negative (TN) and epidermal growth factor 2 (HER2)-positive breast cancer (BC) patients. and currently. there is an unmet need for the treatment of these patients. BM is a complex process that is regulated by the formation of a metastatic niche. https://countryscenesaddleryandpetsuppliers.shop/product-category/pulling-collar/